Evaluation of Genotoxic Effect of Phloxine by Allium Test

Phloxine is used as a food dye. In this study, genotoxicity of phloxine at the root tip Allium cepa L. was investigated. A. meristematic cells were treated with ten different doses phloxine. way, EC50 value determined. Then, applied to tips EC50/2, and EC50×2 doses. Treatment time determined 24, 48 72 hours. As result, it revealed that caused chromosomal aberrations in mitotic cycle cepa. There are equatorial plate shifting metaphase, laggard chromosome, disturbed spindle, chromosome stickiness, C-mitosis, polar among observed aberrations. It stated % aberration index (CAI) increased depending on concentration increase. has been demonstrated highest occurred dose for According research, genotoxic effect For reason, can be emphasized care should taken its use foods.